Product Information
Name:PROTAC ATR degrader-2
Brand:Targetmol
Description:PROTAC ATR degrader-2 (Compound 8i) serves as a PROTAC degrader targeting ATR, effectively degrading it in acute myeloid leukemia (AML) cell lines MV-4-11 and MOLM-13, with DC50 values of 22.9 and 34.5 nM, respectively. This compound induces apoptosis and inhibits the proliferation of AML cells. Additionally, PROTAC ATR degrader-2 demonstrates favorable pharmacokinetic properties and potent antitumor activity in a mouse model of AML.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:743.81
Formula:C40H41N9O6
Color/Form:Solid
Technical inquiry about: PROTAC ATR degrader-2
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