Product Information
Name:TOPOI/PARP-1-IN-1
Brand:Targetmol
Description:Compound B6, also known as TOPOI/PARP-1-IN-1, is a dual inhibitor targeting TOPOI and PARP, exhibiting low cytotoxicity and oral activity with a PARP1 IC 50 of 0.09 μM. This compound effectively inhibits cancer cell proliferation and migration, induces cell cycle arrest at the G0/G1 phase, and triggers apoptosis. In murine models, TOPOI/PARP-1-IN-1 demonstrated a tumor growth inhibition rate (TGI) of 75.4% [1].
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Chemical properties
Molecular weight:718.52
Formula:C36H38Br2N4O2
Color/Form:Solid
Technical inquiry about: TOPOI/PARP-1-IN-1
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