Product Information
Name:G-5758
Brand:Targetmol
Description:G-5758 is an orally active IRE1α inhibitor with an IC50 of 38 nM for XBP1s. It is used in studies involving multiple myeloma models [KMS-11], demonstrating good tolerance in rats at oral doses up to 500 mg/kg. G-5758 exhibits pharmacodynamic effects comparable to those induced by IRE1 knockdown.
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Chemical properties
Molecular weight:588.58
Formula:C27H24F4N6O3S
Color/Form:Solid
Technical inquiry about: G-5758
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