Product Information
Name:VNPP433-3β
Synonyms:
- Galeterone 3β-imidazole
Brand:Targetmol
Description:VNPP433-3β acts as a molecular glue degrader, targeting the androgen receptor (AR) and its splice variants (AR-Vs) as well as MAP kinase-interacting serine/threonine protein kinase Mnk1/2. It effectively inhibits the proliferation of cancer cells LNCaP, C4-2B, and CWR22Rv1, with GI50 values of 0.2, 0.3, and 0.31 μM, respectively. Additionally, VNPP433-3β shows favorable pharmacokinetics in CD-1 mice and suppresses tumor growth in the CWR22Rv1 xenograft mouse model.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:438.61
Formula:C29H34N4
Color/Form:Solid
Technical inquiry about: VNPP433-3β
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