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PX20606

CAS:

Ref. TM-T88353

PX20606
Targetmol

Product Information

Name:PX20606
Synonyms:
  • PX-102
Brand:Targetmol
Description:PX20606 is an orally active farnesoid X receptor (FXR) agonist, demonstrating EC50 values of 220 nM (mFXR) and 50 nM (hFXR) in Gal4-FXR assays. It induces the expression of the tumor suppressor gene NDRG2 and inhibits tumor growth and metastasis in a mouse HCC model. Additionally, PX20606 exhibits hepatoprotective properties.
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Chemical properties

Molecular weight:554.85
Formula:C29H22Cl3NO4
Color/Form:Solid

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