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XM-U-14

Ref. TM-T89347

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Targetmol

Product Information

Name:XM-U-14
Brand:Targetmol
Description:XM-U-14 is a selective PROTAC USP7 degrader that induces the degradation of USP7 in the RS4;11 cell line with a DC50 of 0.74 nM. This compound elevates the levels of p53 and p21, and significantly inhibits the growth of acute lymphoblastic leukemia (ALL) cells, with IC50 values of 0.5 nM in RS4;11 cells and 8.3 nM in Reh cells. Moreover, XM-U-14 induces apoptosis and cell cycle arrest, and effectively inhibits tumor growth.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Color/Form:Odour Solid

Technical inquiry about: XM-U-14

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