Product Information
Name:TQ05310
Synonyms:
- TQ-05310
Brand:Targetmol
Description:TQ05310 is an orally active inhibitor of mutant IDH2, targeting both IDH2-R140Q (IC50=136.9 nM) and IDH2-R172K (IC50=37.9 nM) mutations. This compound suppresses the production of 2-hydroxyglutarate (2-HG) by inhibiting the enzymatic activity of mutant IDH2, and induces differentiation in cells expressing IDH2-R140Q and IDH2-R172K. TQ05310 is utilized in research on acute myeloid leukemia.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:473.38
Formula:C19H17F6N7O
Technical inquiry about: TQ05310
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