SMART1
Ref. TM-T89879
10mg | To inquire | ||
50mg | To inquire |
Product Information
SMART1 is a CRBN-dependent PROTAC with high specificity that effectively degrades Smurf1. It inhibits tumor growth in xenograft models of colorectal cancer (CRC) with KRAS mutations and blocks the PDK1-Akt signaling pathway in KRAS-mutated colorectal cancer.
Chemical properties
Technical inquiry about: TM-T89879 SMART1
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