Product Information
JX237 functions as an inhibitor targeting the epithelial neutral amino acid transporter B 0 AT1 (SLC6A19), exhibiting a potency with an IC 50 of 31 nM. This compound primarily facilitates the absorption of neutral amino acids in the intestines and their reabsorption in the kidneys. The inhibition of B 0 AT1 by JX237 is instrumental in normalizing high levels of plasma amino acids found in rare metabolic amino acid disorders such as phenylketonuria and urea cycle disorders.
Chemical properties
Technical inquiry about: TM-T89913 JX237
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