Product Information
- 2-Phenyl-4-aminopyridine
- 2-Phenyl-4-pyridinamine
- 2-Phenyl-pyridin-4-ylamine
- 4-Pyridinamine, 2-Phenyl-
- Pyridine, 4-amino-2-phenyl-
- 2-Phenylpyridin-4-amine
2-PPA serves as a selective TMEM175 inhibitor (IC 50 =32 μM), primarily influencing lysosomal activity. Through acute inhibition of TMEM175, 2-PPA enhances lysosomal macromolecular catabolism, which in turn boosts macrophage activity and other digestive processes. This compound holds significance in Parkinson's disease research.
Chemical properties
Technical inquiry about: TM-T89916 2-PPA
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