PP5-IN-2
Ref. TM-T89967
Product Information
Name:PP5-IN-2
Brand:Targetmol
Description:PP5-IN-2, a selective and orally active inhibitor of protein phosphatase 5 (PP5), exhibits an IC 50 of 0.9 μM. This compound activates p53 and leads to the downregulation of cyclin D1 and MGMT, thereby inducing cell cycle arrest and reversing Temozolomide (TMZ) resistance in the U87 MG cell line. Additionally, PP5-IN-2 has demonstrated effective inhibition of tumor growth in the xenograft mouse model.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:285.29
Formula:C16H15NO4
Color/Form:Solid
Technical inquiry about: PP5-IN-2
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