KD014
Ref. TM-T9901A-1083
Product Information
Name:KD014
Synonyms:
- DX-2410
- DX-2400
Brand:Targetmol
Description:KD014 (DX-2400) is a human monoclonal antibody (mAb) that targets MMP14, with a Ki of 0.9 nM. It inhibits TGFβ and SMAD2/3 signaling, increases macrophage count and iNOS expression, and shifts macrophage phenotype towards an antitumor M1-like type. KD014 exhibits antitumor activity in three tumor models (MDA-MB-231, MDA-MB-435, and PC3) and is applicable in breast cancer research.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Color/Form:Odour Liquid
Technical inquiry about: KD014
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