Product Information
Name:Zaptuzumab
Synonyms:
- AD5-10
Brand:Targetmol
Description:Zaptuzumab (AD5-10) is a humanized monoclonal antibody targeting death receptor 5 (DR5) with high selective binding affinity. It specifically induces cancer cell death through caspase-mediated apoptosis and autophagic cell death (ACD). Zaptuzumab can activate antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). Additionally, it induces reactive oxygen species (ROS) production and reduces glutathione (GSH) levels. In various xenograft mouse tumor models, Zaptuzumab has demonstrated significant tumor growth inhibition and favorable safety profiles.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Color/Form:Liquid
Technical inquiry about: Zaptuzumab
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