Gigantol
CAS: 67884-30-4
Ref. TM-TL0008
| 1mg | 83.00 € | ||
| 5mg | 169.00 € | ||
| 10mg | 253.00 € | ||
| 25mg | 406.00 € | ||
| 50mg | 556.00 € | ||
| 100mg | 792.00 € | ||
| 1ml*10 (DMSO) | 163.00 € |
Product Information
- Phenol, 5-[2-(3-Hydroxy-5-Methoxyphenyl)Ethyl]-2-Methoxy-
Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a promising neuroprotective agent for successful MSC transplantation in ischemic diseases, it shows the protective effect against hydrogen peroxide-induced apoptosis in rat bone marrow mesenchymal stem cells through the PI3K/Akt pathway.Gigantol inhibits aldose reductase gene to exert its anti-cataract activity. Gigantol induces growth inhibition and apoptosis of HepG2 cells via the PI3K/Akt/NF-κB signaling pathway.Gigantol also shows α-glucosidase inhibitory activity.
Chemical properties
Technical inquiry about: TM-TL0008 Gigantol
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