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Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)
Ref. TM-TMPH-03038
1mg | 2,201.00 € | ||
20µg | 364.00 € | ||
100µg | 670.00 € |
Product Information
- Cobra venom factor, Complement C3 homolog, CVFk, CVF
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely resistant to the actions of complement regulatory factors H (CFH) and I (CFI). Therefore, CVF continuously activates complement resulting in the depletion of complement activity.
Chemical properties
Technical inquiry about: TM-TMPH-03038 Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)
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