LAP (TGF-β 1) Protein, Human, Recombinant (His & Avi), Biotinylated
Ref. TM-TMPJ-00250
| 20µg | 357.00 € | ||
| 100µg | 948.00 € |
Product Information
- transforming growth factor β1, TGFβ, CED, TGFB, TGFbeta, LAP (TGFβ 1), DPD1, LAP (TGFbeta 1), LAP (TGF-β 1), transforming growth factor beta 1, LAP, LAP (TGF-beta 1), TGFB1
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activation of these complexes is a critical step in regulation of TGFβ function in vivo. The TGFβ1 LAP is a ligand for the integrin αvβ6 and that αvβ6-expressing cells induce spatially restricted activition of TGFβ1. And LAP identifies a novel CD4+/CD25+ regulatory T cell subset with TGFbeta-mediated function and enhanced suppression of experimental autoimmune encephalomyelitis.
Chemical properties
Technical inquiry about: TM-TMPJ-00250 LAP (TGF-β 1) Protein, Human, Recombinant (His & Avi), Biotinylated
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