LAIR1 Protein, Human, Recombinant (His & Avi)
Ref. TM-TMPK-00177
| 1mg | 2,863.00 € | ||
| 100µg | 430.00 € | ||
| 500µg | 1,709.00 € |
Product Information
- CD305, LAIR1, LAIR-1, HLAIR1
LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation.
Chemical properties
Technical inquiry about: TM-TMPK-00177 LAIR1 Protein, Human, Recombinant (His & Avi)
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