Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His)
Ref. TM-TMPK-01158
| 1mg | 2,586.00 € | ||
| 100µg | 386.00 € | ||
| 500µg | 1,543.00 € |
Product Information
- SCTE, KLKL2, KLK5, KLK-L2, Klnc, Kallikrein c
The inhibition of kallikrein 5 (KLK5) has been identified as a potential strategy for treatment of the genetic skin disorder Netherton syndrome, in which loss-of-function mutations in the SPINK5 gene lead to down-regulation of the endogenous inhibitor LEKTI-1 and profound skin-barrier defects with severe allergic manifestations. To aid in the development of a medicine for this target, an X-ray crystallographic system was developed to facilitate fragment-guided chemistry and knowledge-based drug-discovery approaches.
Chemical properties
Technical inquiry about: TM-TMPK-01158 Kallikrein 5/KLK5 Protein, Mouse, Recombinant (His)
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