BBOX1 Protein, Human, Recombinant (His & GST)
Ref. TM-TMPY-03756
| 100µg | 689.00 € |
Product Information
- butyrobetaine (γ), 2-oxoglutarate dioxygenase (γ-butyrobetaine hydroxylase) 1, BBOX, butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1, butyroβine (gamma), 2-oxoglutarate dioxygenase (gamma-butyroβine hydroxylase) 1, γ-BBH, gamma-BBH, BBH, G-BBH
BBOX1, also known as gamma-BBH, belongs to thegamma-BBH/TMLD family. It is highly expressed in kidney and moderately expressed in liver. BBOX1 catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation. BBOX1 is an inhibition target for mildronate which can be used to treatanginaandmyocardial infarction. Mildronate may also be beneficial for the treatment ofneurological disorder,diabetes, andseizures andalcohol intoxication.
Chemical properties
Technical inquiry about: TM-TMPY-03756 BBOX1 Protein, Human, Recombinant (His & GST)
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