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ECD Protein, Human, Recombinant (His & GST)
Ref. TM-TMPY-03980
100µg | 588.00 € |
Product Information
- HSGT1, ECD, GCR2, ecdysoneless cell cycle regulator
ECD, also known as ecdysoneless homolog, belongs to the SGT1 family. It is highly expressed in muscle and heart. ECD is a novel promoter of mammalian cell cycle progression. This function is related to its ability to remove the repressive effects of Rb-family tumor suppressors on E2F transcription factors. It is a novel tumor-promoting factor that is differentially expressed in pancreatic cancer and potentially regulates glucose metabolism within cancer cells. ECD may also be a transcriptional activator required for the expression of glycolytic genes.
Chemical properties
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