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4,5-Dimethoxycanthin-6-one
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4,5-Dimethoxycanthin-6-one

CAS: 18110-87-7

Ref. TM-TN3013

1mg
144.00 €
5mg
346.00 €
10mg
558.00 €
25mg
868.00 €
50mg
1,175.00 €
1ml*10 (DMSO)
313.00 €
Estimated delivery in United States, on Friday 10 May 2024

Product Information

Name:
4,5-Dimethoxycanthin-6-one
Synonyms:
  • Methylnigakinone
  • 4,5-Dimethoxy-β-canthin-6-one
  • 6H-Indolo(3,2,1-de)(1,5)naphthyridin-6-one, 4,5-dimethoxy-
  • O-Methylnigakinone
Description:

4,5-Dimethoxycanthin-6-one is an alkaloid isolated from Picrasma quassioides BENNET (Simaroubaceae).4,5-Dimethoxycanthin-6-one was isolated from Picrasma quassioides BENNET (Simaroubaceae) with antimicrobial activity.4,5-Dimethoxycanthin-6-one was isolated from Picrasma quassioides BENNET (Simaroubaceae) with antimicrobial activity. Dimethoxycanthin-6-one is a potent, non-competitive inhibitor of CYP1A2-mediated phenacetin O-deethylation (IC50: 1.7 μM, Ki: 2.6 μM), and a potent inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase.4,5-(4,5-Dimethoxycanthin-6-one) is an alkaloid isolated from Picrasma quassioides BENNET (Simaroubaceae). 4,5-Dimethoxycanthin-6-one has antimicrobial activity against Staphylococcus aureus and its drug-resistant strains.4,5-Dimethoxycanthin-6-one is cytotoxic to the tumor cell lines U937 and HepG2.4,5-Dimethoxycanthin-6-one is a cytotoxicity inhibitor (IC50 : Ki : 6 μM, Ki : 6 μM).

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
280.28
Formula:
C16H12N2O3
Purity:
98.84%
Color/Form:
Solid
MDL:
Melting point:
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Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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