- Angiogenesis
- Apoptosis
- BCL
- Cell Cycle/Checkpoint
- Cyclooxygenase (COX) Inhibitors
- DNA Damage/DNA Repair
- DNA/RNA Synthesis
- ERK
- G-protein Coupled Receptors and 7-TM Receptors
- GPCR/G-Protein
- IL Receptor
- Immunology and Inflammation
- Inhibitors
- JAK/STAT signaling
- JNK
- MAPK
- Microbiology/Virology
- Mmp and Impurities
- NF-κB
- NOS
- Neuroscience
- Prostaglandin Receptor
- Proteases/Proteasome
- STAT
- Stem Cell and Derivatives
- Stem Cells
- TLR
- TNF
- Tyrosine Kinase/Adaptors
- VEGFR
Product Information
- 4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxyphenoxy)-6-methoxy-
- 5,7-Dihydroxy-2-(4-hydroxyphenoxy)-6-methoxy-4H-1-benzopyran-4-one
- 5,7-Dihydroxy-2-(4-hydroxyphenoxy)-6-methoxychromen-4-one
- 5,7-dihydroxy-2-(4-hydroxyphenoxy)-6-methoxy-4H-chromen-4-one
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cells, it inhibits cancer cell growth of osteosarcoma cells by inducing apoptosis accompanied with G0/G1-phase cell cycle arrest and loss in mitochondrial membrane potential.Capillarisin has anti-inflammatory activity, can inhibit LPS-induced inflammation by blocking TLR4-mediated NF-κB and MAPKs activation in BV2 microglia. Capillarisin possesses promising anti-hyperalgesic and anti-allodynic effects through the inhibition of various inflammatory pain signaling.
Chemical properties
Technical inquiry about: TM-TN3587 Capillarisin
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