Product Information
- (1S,2S,6R,6aS,8aR,10aS,10bR,16R,16aS,17R,18aR)-2,3,6,6a,9,10,10a,10b,14,16,16a,17-Dodecahydro-8a,16,17-trihydroxy-2,6a,10b-trimethyl-3-methylene-1,17:2,6-dimethano-8H-naphtho[1,2-f]furo[3,4-b:2,3-c′]bisoxocin-4,8,11,19(1H,8aH)-tetrone
- 1,17:2,6-Dimethano-8H-naphtho[1,2-f]furo[3,4-b:2,3-c']bisoxocin-4,8,11,19(1H,8aH)-tetrone,2,3,6,6a,9,10,10a,10b,14,16,16a,17-dodecahydro-8a,16,17-trihydroxy-2,6a,10b-trimethyl-3-methylene-,[1S-(1a,2b,6b,6aa,8ab,10aa,10bb,16a,16ab,17b,18aS*)]-
- 16,24-Cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid, 14,17-epoxy-7,13,14,20,22-pentahydroxy-1,15-dioxo-, γ-lactone δ-lactone, (7α,14α,16β,22α)-
- 16,24-Cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioicacid, 14,17-epoxy-7,13,14,20,22-pentahydroxy-1,15-dioxo-, g-lactone d-lactone, (7a,14a,16b,22a)-
- 16a,24-Cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioicacid, 14a,17-epoxy-7a,13,14,20,22-pentahydroxy-1,15-dioxo-,g-lactone d-lactone, (20S,22R,24S)- (8CI)
- 16α,24-Cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid, 14α,17-epoxy-7α,13,14,20,22-pentahydroxy-1,15-dioxo-, γ-lactone δ-lactone, (20S,22R,24S)-
Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate cancer cell growth through activation of cell apoptosis and downregulation of androgen receptor expression. Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-κB survival pathway in A375-S2 cells.
Chemical properties
Technical inquiry about: TM-TN4774 Physalin A
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