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Lentztrehalose A

CAS:

Ref. TM-TN7283

Lentztrehalose A
Targetmol

Product Information

Name:Lentztrehalose A
Brand:Targetmol
Description:Lentztrehalose A, a disaccharide microbial metabolite identified in Lentzea, exhibits a range of biological activities. This compound specifically inhibits M. smegmatis trehalase—an enzyme involved in trehalose metabolism—more effectively than trehalase from porcine kidney, with IC50 values of 0.67 mM and >20 mM, respectively. Additionally, Lentztrehalose A at a concentration of 100 mM promotes autophagy in MeWo melanoma and OVK18 ovarian cancer cells. When administered at 50 mg/kg daily, it enhances survival rates and impedes tumor growth in a Sarcoma 180 murine sarcoma model.
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Chemical properties

Molecular weight:444.43
Formula:C17H32O13
Color/Form:Solid

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