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(−)-Voacangarine

CAS:

Ref. TM-TN7544

(−)-Voacangarine
Targetmol

Product Information

Name:(−)-Voacangarine
Synonyms:
  • NSC 306219
  • (−)-Voacristine
Brand:Targetmol
Description:(–)-Voacangarine, an indole alkaloid isolated from V. africana, exhibits cytotoxicity towards various cell lines including HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 with IC50 values of 20 µg/ml. Additionally, it demonstrates cytostatic effects on wild-type S. cerevisiae and is cytotoxic to Δrad3-e5 and Δrad6-1 mutant strains of S. cerevisiae, which have defects in DNA strand break repair and the mutagenic repair pathway, respectively.
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Chemical properties

Molecular weight:384.47
Formula:C22H28N2O4
Color/Form:Solid

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