Product Information
- 21-Desoxycortisone
- 17-Alpha-Hydroxypregn-4-Ene-3,11,20-Trione
- 17-Hydroxypregn-4-Ene-3,11,20-Trione
- 17α-Hydroxy-11-oxoprogesterone
- 17α-Hydroxypregn-4-ene-3,11,20-trione
- 21-Deoxycortisone
- 4-Pregnene-17α-ol-3,11,20-trione
- 6-Pregn-4-en-17α-ol-3,11,20-trione
- NSC 38722
- Pregn-4-ene-3,11,20-trione, 17-hydroxy-
- See more synonyms
21-Deoxy Cortisone (21-Desoxycortisone; NSC 38722) is a corticosteroid metabolite of 11-ketoprogesterone. It is generated from 11-ketoprogesterone by the cytochrome P450 (CYP) isoform CYP17A1, and can also be produced by oxidation via 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) from 21-deoxycorticosterone. In patients with congenital adrenal hyperplasia, a metabolic disorder characterized by a deficiency of 21-hydroxylase, levels of 21-Deoxy Cortisone are elevated.
Chemical properties
Technical inquiry about: TM-TN8231 21-Deoxy Cortisone
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