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Cholesterol sulfate

CAS:

Ref. TM-TN8971

Cholesterol sulfate
Targetmol

Product Information

Name:Cholesterol sulfate
Synonyms:
  • Cholesterol 3-sulfate
Brand:Targetmol
Description:Cholesterol sulfate is a multifunctional endogenous sterol sulfate and selective DOCK2 inhibitor with an IC50 of 2 μM in mouse assays. Cholesterol sulfate plays multiple roles including in epidermal barrier formation by regulating keratinocyte differentiation and corneocyte desquamation, functions as a serine-protease inhibitor, acts as a glucocorticoid receptor antagonist, and activates RORα/γ in the thymus. Cholesterol sulfate serves as a critical research tool for investigating cutaneous biology, immunomodulation, steroid metabolism, sperm capacitation, platelet aggregation, and disorders such as X-linked ichthyosis.
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Chemical properties

Molecular weight:466.72
Formula:C27H46O4S
Purity:97%
Color/Form:Solid

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