Product Information
Name:C14-490
Brand:Targetmol
Description:C14-490 is an ionizable cationic lipid (pKa= 5.94) utilized in the synthesis of lipid nanoparticles (LNPs). These LNPs serve as a platform for subsequent gene editing studies in hematopoietic stem cells (HSCs) in utero. C14-490 LNPs encapsulate SpCas9 mRNA and TTR sgRNA, employing an optimized B5 formulation parameter, and are further enhanced by the surface attachment of CD45 antibody F(ab’)2 fragments to create Systemically Targeted Editing Mechanism LNPs (STEM LNPs).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:1393.35
Formula:C86H177N5O7
Color/Form:Solid
Technical inquiry about: C14-490
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