Product Information
Name:Fmoc-PEG6-Val-Cit-PAB-OH
Brand:Targetmol
Description:Fmoc-PEG6-Val-Cit-PAB-OH is a cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzyl alcohol on PAB can be utilized to attach reactive groups (e.g., PNP) for drug payload conjugation. The Fmoc protecting group is removable with piperidine, revealing a primary amine for amide bond formation in conjugation reactions. The Val-Cit-PAB segment is cleaved by cellular proteases, enabling efficient payload release into cells.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:937.086
Formula:C48H68N6O13
Color/Form:Solid
Technical inquiry about: Fmoc-PEG6-Val-Cit-PAB-OH
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