Product Information
Name:Fmoc-PEG2-Val-Cit-PAB-OH
Brand:Targetmol
Description:Fmoc-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker that features a Boc-protected amine, hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzyl alcohol on the PAB can be used for conjugating reactive groups (e.g., PNP) to attach a payload. The Fmoc protecting group is removable with piperidine, revealing a primary amine for amide bond formation in conjugation reactions. The Val-Cit-PAB segment is cleaved by cellular proteases to efficiently release the payload inside cells.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:760.876
Formula:C40H52N6O9
Color/Form:Solid
Technical inquiry about: Fmoc-PEG2-Val-Cit-PAB-OH
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