Product Information
Name:Boc-PEG2-Val-Cit-PAB-OH
Brand:Targetmol
Description:Boc-PEG2-Val-Cit-PAB-OH is an enzymatically cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer, and a Val-Cit-PAB dipeptide. The benzyl alcohol on PAB can be utilized for attachment to reactive groups (such as PNP) to connect with a drug payload. The Boc protecting group can be removed with acid, revealing a primary amine that serves for coupling reactions to form an amide. The Val-Cit-PAB segment is cleaved by cellular proteases, facilitating the effective release of the payload inside the cell.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:638.753
Formula:C30H50N6O9
Color/Form:Solid
Technical inquiry about: Boc-PEG2-Val-Cit-PAB-OH
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