Product Information
Name:ABT 888
Controlled Product
Synonyms:
- 1H-Benzimidazole-7-carboxamide
- 2-[(2R)-2-methyl-2-pyrrolidinyl]-
- 1H-Benzimidazole-4-carboxamide
- 2-[(2R)-2-methyl-2-pyrrolidinyl]- (9CI)
- 2-[(2R)-2-Methyl-2-pyrrolidinyl]-1H-benzimidazole-7-carboxamide
- 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-1,3-benzodiazole-4-carboxamide
- 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide
- A 861695
- Veliparib
- Veliparib ER
Brand:TRC
Description:Applications ABT-888 is a potent, orally bioavailable PARP-1/-2 inhibitor shown to potentiate DNA damaging agents. The ability to potentiate temozolomide (TMZ) and develop a biological marker for PARP inhibition was evaluated in vivo. Potent PARP inhibitor.References Virag, L., et al.: Pharmacol. Rev., 54, 375 (2002), Tentori, L., et al.: Clin. Cancer Res., 9, 5370 (2003), Kim, M., et al.: Cell, 119, 803 (2004), Tentori, L., et al.: Pharmacol. Res., 52, 25 (2005),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:244.29
Formula:C13H16N4O
Color/Form:Neat
InChI:InChI=1S/C13H16N4O/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17)/t13-/m1/s1
InChI key:InChIKey=JNAHVYVRKWKWKQ-CYBMUJFWSA-N
SMILES:C[C@]1(c2nc3cccc(C(N)=O)c3[nH]2)CCCN1
Technical inquiry about: ABT 888
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.