Estimated delivery in United States, on Tuesday 25 Jun 2024
Product Information
Name:
AC 220
Controlled Product
Synonyms:
- AC 010220
- Quizartinib
- N-(5-tert-Butylisoxazol-3-yl)-N'-[4-[7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl]urea
- Ac 010220
- Ac-220
- N-(5-tert-Butylisoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-ylethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea
- N-[5-(1,1-Dimethylethyl)-3-isoxazolyl]-N′-[4-[7-[2-(4-morpholinyl)ethoxy]imidazo[2,1-b]benzothiazol-2-yl]phenyl]urea
CAS:
Description:
Applications AC 220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML).
References Zarrinkar, P., et al.: Blood, 114, 2984 (2009); Sato, T., et al.: Blood, 117, 3286 (2011)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
560.67
Formula:
C29H32N6O4S
Color/Form:
White Solid
InChI:
InChI=1S/C29H32N6O4S/c1-29(2,3)25-17-26(33-39-25)32-27(36)30-20-6-4-19(5-7-20)22-18-35-23-9-8-21(16-24(23)40-28(35)31-22)38-15-12-34-10-13-37-14-11-34/h4-9,16-18H,10-15H2,1-3H3,(H2,30,32,33,36)
InChI key:
InChIKey=CVWXJKQAOSCOAB-UHFFFAOYSA-N
SMILES:
CC(C)(C)c1cc(=NC(=O)Nc2ccc(-c3cn4c(n3)sc3cc(OCCN5CCOCC5)ccc34)cc2)[nH]o1
MDL:
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EINECS:
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HS code:
Technical inquiry about: TR-A115000 AC 220
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