4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid, Sodium Salt

CAS: 51023-76-8

Ref. TR-A158450

Product Information

• Name: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid, Sodium Salt
• Synonyms: disodium;5-acetamido-2-[(E)-2-(4-isothiocyanato-2-sulfonatophenyl)ethenyl]benzenesulfonate, SITS, Disodium 4-acetamido-4′-isothiocyanatostilbene-2,2′-disulfonate, Benzenesulfonic acid, 5-(acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]-, disodium salt, Benzenesulfonic acid, 5-(acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]-, sodium salt (1:2)

Description

Stability Hygroscopic, Temperature Sensitive
Applications A fluorescent label for the specific and reversible labelling of the outer components of the plasma membrane. The reagent reacts with a fixed number of sites on the surface of cells concerned with anion permeation; does not pass through the osmotic barrier of the membrane; reacts under physiological conditions of temperature, pH and tonicity; and is detectable in small amounts. SEE ALSO NOTES FOR DIDS (CAT#D460600).Fluorescence: max. Abs. l = 336nm, max. Em. l = 436 nm.
References Maddy., A.H.: Biochim. Biophys. Acta., 88, 390 (1964), Cabantchik, Z.I., et al.: J. Membrane Biol., 10, 311 (1972); Am. J. Physiol. 262, C803 (1992); J. Biol. Chem. 266, 13355 (1991), Ma, W., et al.: J. Pharmacol. Exp. Ther., 328, 409 (2009),

• Brand: TRC

Chemical properties

• Molecular weight: 498.46
• Formula: C₁₇H₁₂N₂O₇S₃Na
• Color/Form: Neat
• InChI: InChI=1S/C17H14N2O7S3.2Na/c1-11(20)19-15-7-5-13(17(9-15)29(24,25)26)3-2-12-4-6-14(18-10-27)8-16(12)28(21,22)23;;/h2-9H,1H3,(H,19,20)(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2/b3-2+
• InChI key: InChIKey=NPAWAMRXPHRVQY-WTVBWJGASA-L
• SMILES: CC(=O)Nc1ccc(/C=C/c2ccc(N=C=S)cc2S(=O)(=O)O[Na])c(S(=O)(=O)O[Na])c1