1-Acetyl-5-(2-aminopropyl)indoline-7-carbonitrile
CAS:
Ref. TR-A168385
250mg
204.00€
2500mg
1,479.00€
Product Information
Name:1-Acetyl-5-(2-aminopropyl)indoline-7-carbonitrile
Controlled Product
Synonyms:
- 1-Acetyl-5-(2-aminopropyl)-2,3-dihydro-1H-Indole-7-carbonitrile
Brand:TRC
Description:Applications 1-Acetyl-5-(2-aminopropyl)indoline-7-carbonitrile is an intermediate in the synthesis of Silodosin (S465000), an α1a-adrenoceptor antagonist. It is used in treatment of benign prostatic hypertophy.References Barve, I.J., et. al.: Tetrahedron, 69, 2834 (2013); Shibata, K., et al.: Mol. Pharmacol., 48, 250 (1995); Murata, S., et al.: J. Urol., 164, 578 (2000)
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Chemical properties
Molecular weight:243.31
Formula:C14H17N3O
Color/Form:Neat
InChI:InChI=1S/C14H17N3O/c1-9(16)5-11-6-12-3-4-17(10(2)18)14(12)13(7-11)8-15/h6-7,9H,3-5,16H2,1-2H3
InChI key:InChIKey=FZBIESPTFIVNEJ-UHFFFAOYSA-N
SMILES:CCCCCCCCCC(=O)OCC1CO1
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