21-O-Acetyl Dexamethasone-d5

CAS: 1177-87-3

Ref. TR-A168482

Product Information

• Name: 21-O-Acetyl Dexamethasone-d5
• Synonyms: (11ß,16a)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione-d5, 9-Fluoro-11ß,17,21-trihydroxy-16a-methyl-pregna-1,4-diene-3,20-dione 21-Acetate-d5, Decadronal-d5, Dectancyl-d5, Dex-Cortidelt Acetate-d5, Dexa-Cortisyl-d5, NSC 39471-d5, (11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate, (11Beta,16Alpha)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Acetate, (11β,16α)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione, (16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate, (8Xi,11Beta,14Xi,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate, 16α-Methyl-9α-fluoroprednisolone 21-acetate, Dalalone DP, Dalalone LA, Decadron LA, Decadronal, Dectancyl, Dex-Cortidelt acetate, Dexa-Cortisyl, Dexamethasone Acetate, Dexamethasone-17-acetate, Dexamethasoneacetate, Fortecortin, Fortecortin (crystal suspension), NSC 39471, Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-acetate

Description

Applications Isotope labelled intermediate in the synthesis of Dexamethasone (D298800), a glucocorticoid anti-inflammatory agent.
References Liu, Y., et al.: Anal. Bioanal. Chem., 395, 591 (2009), Rodgers, A., et al.: Chem. Res. Toxicol., 23, 724 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

• Brand: TRC

Chemical properties

• Molecular weight: 439.53
• Formula: C₂₄D₅H₂₆FO₆
• Color/Form: Neat
• InChI: InChI=1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1/i5D2,10D,12D2
• InChI key: InChIKey=AKUJBENLRBOFTD-DNSVMMNRSA-N
• SMILES: [2H]C1=C2C([2H])([2H])C[C@H]3[C@@H]4C[C@@H](C)[C@](O)(C(=O)C([2H])([2H])OC(C)=O)[C@@]4(C)C[C@H](O)[C@]3(F)[C@@]2(C)C=CC1=O