(2S)-2-(Acetylamino)-3-hydroxy-N-(phenylmethyl)propanamide

CAS: 171623-03-3

Ref. TR-A171625

Product Information

• Name: (2S)-2-(Acetylamino)-3-hydroxy-N-(phenylmethyl)propanamide
• Synonyms: Propanamide, 2-(acetylamino)-3-hydroxy-N-(phenylmethyl)-, (2S)-, Propanamide, 2-(acetylamino)-3-hydroxy-N-(phenylmethyl)-, (S)-, (2S)-2-(Acetylamino)-N-benzyl-3-hydroxypropanamide
• Brand: TRC
• Description: Applications (2S)-2-(Acetylamino)-3-hydroxy-N-(phenylmethyl)propanamide is an intermediate in the synthesis of Epi-Lacosamide (E588795), which is an impurity of Lacosamide (L098500), a medication used for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain. Lacosamide is a potent anticonvulsant.References Choi, D., et al.: J. Med. Chem., 39, 1907 (1996), Morieux, P., et al.: Bioorg. Med. Chem., 16, 8968 (2008),

Chemical properties

• Molecular weight: 236.267
• Formula: C₁₂H₁₆N₂O₃
• Color/Form: Neat
• InChI: InChI=1S/C12H16N2O3/c1-9(16)14-11(8-15)12(17)13-7-10-5-3-2-4-6-10/h2-6,11,15H,7-8H2,1H3,(H,13,17)(H,14,16)/t11-/m0/s1
• InChI key: InChIKey=XRKSCJLQKGLSKU-NSHDSACASA-N
• SMILES: CC(=O)N[C@@H](CO)C(=O)NCc1ccccc1