(3E)-1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylic Acid Methyl Ester
CAS: 1168152-06-4
Ref. TR-A173865
| 10mg | 196.00 € | ||
| 50mg | 855.00 € | ||
| 100mg | 1,472.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Product Information
Name:
(3E)-1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylic Acid Methyl Ester
Controlled Product
Synonyms:
- 1H-Indole-6-carboxylic acid
- 1-acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-
- methyl ester
- (3E)- (ACI)
- Methyl (3E)-1-acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylate (ACI)
Description:
Applications (3E)-1-Acetyl-3-(ethoxyphenylmethylene)-2,3-dihydro-2-oxo-1H-indole-6-carboxylic Acid Methyl Ester is an impurity of Intedanib (I666650), an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases.
References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
365.379
Formula:
C21H19NO5
Color/Form:
Neat
InChI:
InChI=1S/C21H19NO5/c1-4-27-19(14-8-6-5-7-9-14)18-16-11-10-15(21(25)26-3)12-17(16)22(13(2)23)20(18)24/h5-12H,4H2,1-3H3/b19-18+
InChI key:
InChIKey=GIIOASILGOFVPI-UHFFFAOYSA-N
SMILES:
CC(Cc1ccc(O)c(O)c1)C(=O)O
MDL:
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EINECS:
Merck:
HS code:
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