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Product Information
Name:
1-Acetyl-4-(4-hydroxyphenyl)piperazine
Controlled Product
Synonyms:
- 1-[4-(4-Hydroxyphenyl)-1-piperazinyl]ethanone
- 4-(4-Acetylpiperazino)phenol
- 1-Acetyl-4-(p-hydroxyphenyl)piperazine
- Ketoconazole Intermediate (branched chain of ketoconazole)
- 1-Acetyl-4-(4hydroxyphenyl)piperazine
- 1-[4-(4-Hydroxyphenyl)Piperazin-1-Yl]Ethanone
- 1-[4-(4-Hydroxyphenyl)piperazin-1-yl]ethan-1-one
- 4-(1-Acetylpiperazin-4-yl)phenol
- 4-(4-Acetyl-1-piperazino)phenol
- 4-(4-Acetylpiperazin-1-yl)phenol
- See more synonyms
- 4-(4-Acetylpiperazin-4-Yl)Phenol
- Ethanone, 1-[4-(4-hydroxyphenyl)-1-piperazinyl]-
- Piperazine, 1-acetyl-4-(4-hydroxyphenyl)-
- T 1141
- Tetraethoxy C methyl propane
CAS:
Description:
Applications 1-Acetyl-4-(4-hydroxyphenyl)piperazine is an intermediate used to prepare Ketoconazole (K186000) which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo.
References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
220.27
Formula:
C12H16N2O2
Color/Form:
White
InChI:
InChI=1S/C12H16N2O2/c1-10(15)13-6-8-14(9-7-13)11-2-4-12(16)5-3-11/h2-5,16H,6-9H2,1H3
InChI key:
InChIKey=AGVNLFCRZULMKK-UHFFFAOYSA-N
SMILES:
CC(=O)N1CCN(c2ccc(O)cc2)CC1
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TR-A179045 1-Acetyl-4-(4-hydroxyphenyl)piperazine
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