Product Information
Name:1-Acetyl-4-(4-hydroxyphenyl)piperazine
Controlled Product
Synonyms:
- 1-[4-(4-Hydroxyphenyl)-1-piperazinyl]ethanone
- 4-(4-Acetylpiperazino)phenol
- 1-Acetyl-4-(p-hydroxyphenyl)piperazine
- Ketoconazole Intermediate (branched chain of ketoconazole)
Brand:TRC
Description:
Applications 1-Acetyl-4-(4-hydroxyphenyl)piperazine is an intermediate used to prepare Ketoconazole (K186000) which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo.
References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:220.27
Formula:C12H16N2O2
Color/Form:Neat
InChI:InChI=1S/C12H16N2O2/c1-10(15)13-6-8-14(9-7-13)11-2-4-12(16)5-3-11/h2-5,16H,6-9H2,1H3
InChI key:InChIKey=AGVNLFCRZULMKK-UHFFFAOYSA-N
SMILES:CC(=O)N1CCN(c2ccc(O)cc2)CC1
Technical inquiry about: 1-Acetyl-4-(4-hydroxyphenyl)piperazine
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