1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone
CAS: 1801881-15-1
Ref. TR-A180180
| 500mg | 1,060.00 € |
Product Information
- 1-(4-aminophenyl)-5-chloro-2,3-dihydropyridin-6-one
Applications 1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone is an impurity of Apixaban (A726700(P)), which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. Apixaban is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.
References Luettgen, J. M., et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T., et al.: J. Thromb. Thrombol., 31, 310 (2011); Barrett, Y. C., et al.: Thromb. Haemos., 105, 181 (2011);
Chemical properties
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