1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone
CAS:
Ref. TR-A180180
500mg
1,022.00€
Product Information
Name:1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone
Controlled Product
Synonyms:
- Apixaban Impurity
Brand:TRC
Description:Applications 1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone is an impurity of Apixaban (A726700(P)), which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. Apixaban is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.References Luettgen, J. M., et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T., et al.: J. Thromb. Thrombol., 31, 310 (2011); Barrett, Y. C., et al.: Thromb. Haemos., 105, 181 (2011);
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Chemical properties
Molecular weight:222.671
Formula:C11H11ClN2O
Color/Form:Neat
InChI:InChI=1S/C11H11ClN2O/c12-10-2-1-7-14(11(10)15)9-5-3-8(13)4-6-9/h2-6H,1,7,13H2
InChI key:InChIKey=HVHHXVHBWVUZAP-UHFFFAOYSA-N
SMILES:Nc1ccc(N2CCC=C(Cl)C2=O)cc1
Technical inquiry about: 1-(4-Aminophenyl)-3-chloro-5,6-dihydro-2(1H)-pyridinone
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