Nα-Acetyl-L-Lysine

CAS: 1946-82-3

Ref. TR-A185540

Product Information

• Name: Nα-Acetyl-L-Lysine
• Synonyms: 6-Amino-L-2-acetamidohexanoic Acid, N2-Acetyl-L-lysine, N2-Acetyllysine, N-Acetyl-L-lysine, Na-Acetyllysine, (2S)-2-Acetamido-6-aminohexanoic acid, (2S)-6-Amino-2-acetamidohexanoic acid, 6-Amino-<span class="text-smallcaps">L</span>-2-acetamidohexanoic acid, <span class="text-smallcaps">L</span>-Lysine, N²-acetyl-, Ac-Lys-Oh, Lysine, N²-acetyl-, <span class="text-smallcaps">L</span>-, N(alpha)-Acetyllysine, N-Acetyl-<span class="text-smallcaps">L</span>-lysine, N-acetyl-L-lysine, N-alpha-Acetyl-L-lysine, N²-Acetyl-<span class="text-smallcaps">L</span>-lysine, N²-Acetyllysine, N^α-Acetyl-<span class="text-smallcaps">L</span>-lysine, N^α-Acetyllysine, N~2~-acetyl-L-lysine, Nα-Acetyl-L-lysine, Lysine, N2-acetyl-, L-, Nα-Acetyllysine, L-Lysine, N2-acetyl-

Description

Applications Nα-Acetyl-L-Lysine is an antibacterial lysine analogue that targets lysine riboswitches. Nα-Acetyl-L-Lysine is used in the metabolomic characterization of ovarian epithelial carcinomas which allows for better therapeutic management of patients. The presence of Nα-Acetyl-L-Lysine and other N-acetylated amino acids in the urine can be used to detect aminoacylase I deficiency.
References Gerlo, E. et al.: Anal. Chim. Acta, 571, 191 (2006); Ben Sellem, D. et al.: J. Oncol., 174019, 9 (2011); Blount, K.F. et al.: Nat. Chem. Biol., 3, 44 (2007);

• Brand: TRC

Chemical properties

• Molecular weight: 188.22
• Formula: C₈H₁₆N₂O₃
• Color/Form: Neat
• InChI: InChI=1S/C8H16N2O3/c1-6(11)10-7(8(12)13)4-2-3-5-9/h7H,2-5,9H2,1H3,(H,10,11)(H,12,13)/t7-/m0/s1
• InChI key: InChIKey=VEYYWZRYIYDQJM-ZETCQYMHSA-N
• SMILES: CC(=O)N[C@@H](CCCCN)C(=O)O