2'-Acetylneriifolin

CAS: 25633-33-4

Ref. TR-A187010

Product Information

• Name: 2'-Acetylneriifolin
• Synonyms: [(2S,3S,4S,5S,6R)-5-hydroxy-6-[[(3S,5R,8R,9S,10S,13R,14S,17R)-14-hydroxy-10,13-dimethyl-17-(5-oxo-2H-furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-4-methoxy-2-methyloxan-3-yl] acetate, (3b,5b)-3-((2-O-Acetyl-6-deoxy-3-O-methyl-a-L-glucopyranosyl)oxy)-14-hydroxycard-20(22)-endolide, (3β,5β)-3-[(2-O-Acetyl-6-deoxy-3-O-methyl-α-<span class="text-smallcaps">L</span>-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide, 25633-33-4, 2′-Acetylneriifolin, Acetylneriifolin, Card-20(22)-enolide, 3-[(2-O-acetyl-6-deoxy-3-O-methyl-α-<span class="text-smallcaps">L</span>-glucopyranosyl)oxy]-14-hydroxy-, (3β,5β)-, Cerberin, Monoacetylneriifolin, Neriifolin, 2′-acetate, Neriifolin-monoacetat, Pveneniferin, Veneniferin, card-20(22)-enolide, 3-[(2-O-acetyl-6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy]-14-hydroxy-, (3beta,5beta)-

Description

Applications 2'-Acetylneriifolin is a cytotoxic cardenolide glycoside with possible cytotoxic activities against oral human epidermoid carcinoma (KB), human breast cancer cell (BC) and human small cells lung cancer (NCI-H187).
References Cheenpracha, S., et al.: Chem. Pharma. Bull., 52, 1023 (2004)

• Brand: TRC

Chemical properties

• Molecular weight: 576.72
• Formula: C₃₂H₄₈O₉
• Color/Form: Neat
• InChI: InChI=1S/C32H48O9/c1-17-27(40-18(2)33)28(37-5)26(35)29(39-17)41-21-8-11-30(3)20(15-21)6-7-24-23(30)9-12-31(4)22(10-13-32(24,31)36)19-14-25(34)38-16-19/h14,17,20-24,26-29,35-36H,6-13,15-16H2,1-5H3/t17-,20+,21-,22+,23-,24+,26-,27-,28-,29-,30-,31+,32-/m0/s1
• InChI key: InChIKey=UYQMTWMXBKEHJQ-WVDDWMFZSA-N
• SMILES: COC1C(OC(C)=O)C(O[C@H]2CC[C@]3(C)[C@H]4CC[C@]5(C)[C@@H](C6=CC(=O)OC6)CC[C@]5(O)[C@@H]4CC[C@@H]3C2)O[C@@H](C)[C@@H]1O