N1-Acetylspermine-d3 Trihydrochloride

CAS: 77928-70-2

Ref. TR-A188007

Product Information

• Name: N1-Acetylspermine-d3 Trihydrochloride
• Synonyms: N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]acetamide-d3 Trihydrochloride, N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]acetamide-d3 Hydrochloride (1:3), acetamide, N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-, N-[3-({4-[(3-Aminopropyl)amino]butyl}amino)propyl]acetamid

Description

Applications N1-Acetylspermine-d3 Trihydrochloride is the isotope labelled analog of N1-Acetylspermine Trihydrochloride (A188005); a monoacetylated derivative of Spermine (S680510) which is a biogenic polyamine formed from Spermidine (S680400) that occurs in almost all tissues. Spermine is also essential for both normal and neoplastic tissue growth and is involved in the modulation of calcium-dependent immune processes.
References Israel, et al.: J. Med. Chem., 7, 710 (1964); Janne, J., et al.: Biochim. Biophys. Acta, 473, 241 (1978); Theoharides, T.C., et al.: Life Sci., 27, 703 (1980); Horn, Y., et al.: Cancer Res., 42, 3248 (1982)

• Brand: TRC

Chemical properties

• Molecular weight: 356.78
• Formula: C₁₂H₂₈D₃Cl₃N₄O
• Color/Form: Neat
• InChI: InChI=1S/C12H28N4O/c1-12(17)16-11-5-10-15-8-3-2-7-14-9-4-6-13/h14-15H,2-11,13H2,1H3,(H,16,17)/i1D3
• InChI key: InChIKey=GUNURVWAJRRUAV-FIBGUPNXSA-N
• SMILES: [2H]C([2H])([2H])C(=O)NCCCNCCCCNCCCN