Aclidinium Bromide

CAS: 320345-99-1

Ref. TR-A190180

Product Information

• Name: Aclidinium Bromide
• Synonyms: 1-Azoniabicyclo[2.2.2]octane, 3-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-, bromide (1:1), (3R)-, 1-Azoniabicyclo[2.2.2]octane, 3-[(hydroxydi-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-, bromide, (3R)- (9CI), (3R)-(2-Hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide, Genuair, LAS 34273, LAS-W 330, 1-Azoniabicyclo[2.2.2]octane, 3-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-, bromide (1:1), (3R)-, 1-Azoniabicyclo[2.2.2]octane, 3-[(hydroxydi-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-, bromide, (3R)-, Acridinium Bromide, Bretaris Genuair, Eklira Genuair, Las 34273, Las-W 330, Aclidinium bromide

Description

Applications Aclidinium Bromide is a novel long-acting antimuscarinic bronchodilator in phase II clinical trials for the treatment of chronic obstructive pulmonary disease (1,2).
References (1) Gupta, V. and Singh, D.: Expert Rev Respir Med. 6, 581 (2012) (2) De La Motte, S., et al.: Int. J. Clin. Pharmacol. Therap., 50,403 (2012)

• Brand: TRC

Chemical properties

• Molecular weight: 564.55
• Formula: C₂₆H₃₀NO₄S₂·Br
• Color/Form: Neat
• InChI: InChI=1S/C26H30NO4S2.BrH/c28-25(26(29,23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21;/h1-5,7-10,17-18,20,22,29H,6,11-16,19H2;1H/q+1;/p-1/t20-,22-,27?;/m0./s1
• SMILES: O=C(O[C@H]1C[N@+]2(CCCOc3ccccc3)CC[C@H]1CC2)C(O)(c1cccs1)c1cccs1.[Br-]