1-Adamantanemethanol

CAS: 770-71-8

Ref. TR-A208125

Product Information

• Name: 1-Adamantanemethanol
• Synonyms: Tricyclo[3.3.1.13,7]decane-1-methanol, (Adamantan-1-yl)methanol, 1-(Hydroxymethyl)adamantane, 1-Adamantylcarbinol, 1-Adamantylmethanol, 3-(Hydroxymethyl)adamantane, 1-Adamantane Methanol, 1-Tricyclo[3.3.1.1(3,7)]decanemethanol, Tricyclo(3.3.1.13,7)Dec-1-Ylmethanol, Tricyclo[3.3.1.1^3,7]decane-1-methanol, Tricyclo[3.3.1.1~3,7~]Dec-1-Ylmethanol

Description

Applications 1-Adamantanemethanol is used as a reagent in the synthesis of adamantane and noradamantane based histone deacetylase (HDAC) inhibitors for the treatment of cancer. It is also used as a reagent in the synthesis of (1-adamantyl)methyl glycidyl ether, a versatile building block for living polymerization.
References Gopalan, B., et al.: Bioorg. Med. Chem. Lett., 23, 2532 (2013); Suzuki, T., et al.: J. Med. Chem., 55, 9562 (2012); Moers, C., et al.: Macromol. Rapid Comm., 35, 1075 (2014)

• Brand: TRC

Chemical properties

• Molecular weight: 166.26
• Formula: C₁₁H₁₈O
• Color/Form: Neat
• InChI: InChI=1S/C11H18O/c12-7-11-4-8-1-9(5-11)3-10(2-8)6-11/h8-10,12H,1-7H2/t8-,9+,10-,11?
• InChI key: InChIKey=MDVGOOIANLZFCP-QGYQLCJMSA-N
• SMILES: OCC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3