Product Information
Name:AdipoRon
Synonyms:
- 2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide
- 2-(4-Benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide
Brand:TRC
Description:Applications AdipoRon is an AdipoR agonist and activates AMPK and PPAR-α pathways in the muscle and liver. AdipoRon ameliorated diabetes of genetically obese rodent model db/db mice, and prolonged the shortened lifespan of db/db mice on a high-fat diet. AdipoRon is a promising therapeutic approach for the treatment of obesity-related diseases such as type 2 diabetes.References Okada-Iwabu, M., et. al.: Nature, 503, 493 (2013)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:428.52
Formula:C27H28N2O3
Color/Form:Neat
InChI:InChI=1S/C27H28N2O3/c30-26(28-24-15-17-29(18-16-24)19-21-7-3-1-4-8-21)20-32-25-13-11-23(12-14-25)27(31)22-9-5-2-6-10-22/h1-14,24H,15-20H2,(H,28,30)
InChI key:InChIKey=SHHUPGSHGSNPDB-UHFFFAOYSA-N
SMILES:O=C(COc1ccc(C(=O)c2ccccc2)cc1)NC1CCN(Cc2ccccc2)CC1
Technical inquiry about: AdipoRon
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