AH 13205

CAS: 148436-63-9

Ref. TR-A434600

Product Information

• Name: AH 13205
• Synonyms: (1R,2S)-2-[4-(1-Hydroxyhexyl)phenyl]-5-oxo-cyclopentaneheptanoic Acid

Description

Applications AH 13205 is a selective prostanoid EP2-receptor agonist and is known to exhibit neuroprotective properties. Competes with PGE2, Prostaglandin E2 for binding, Prostanoid Receptor agonist. Showed promising activity in guinea pigs but was not effective to show bronchodilator activity in humans.
References Guan Y, et al. 2002. BMC Pharmacol. Jun 27;2:14 >Hillock CJ, et al. 1999. Eur J Pharmacol. 1999 Jul 28;378(1):99-108Nials AT, et al. 1993. Cardiovasc Drug Rev;11:165–79James B, et al. 2011. Thorax. Dec; 66(12): 1029–1035

• Brand: TRC

Chemical properties

• Molecular weight: 388.54
• Formula: C₂₄H₃₆O₄
• Color/Form: Neat
• InChI: InChI=1S/C24H36O4/c1-2-3-6-10-22(25)19-14-12-18(13-15-19)20-16-17-23(26)21(20)9-7-4-5-8-11-24(27)28/h12-15,20-22,25H,2-11,16-17H2,1H3,(H,27,28)