Almotriptan N-Di-methyl Dimer Malate

CAS: 154323-57-6

Ref. TR-A440015

Product Information

• Name: Almotriptan N-Di-methyl Dimer Malate
• Synonyms: 2-(2-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-5-((pyrrolidin-1-ylsulfonyl)methyl)-1H-indol-3-yl)-N,N-dimethylethanamine 2-Hydroxysuccinate, 1-[[3-(2-Dimethylaminoethyl)-5-Indolyl]Methanesulphonyl]Pyrrolidine Malate, 1-[[[2-(Dimethyl-Amino)Ethyl]-1H-Indol-5-Yl]Methyl]Sulfonyl]Pyrrolidine Malate, 1H-Indole-3-ethanamine, N,N-dimethyl-5-[(1-pyrrolidinylsulfonyl)methyl]-, 2-hydroxybutanedioic acid - N,N-dimethyl-2-{5-[(pyrrolidin-1-ylsulfonyl)methyl]-1H-indol-3-yl}ethanamine (1:1), Almogran, Almotriptan Malate, Almotriptan Maleate, Almotriptanmaleate, Butanedioic acid, hydroxy-, compd with 1-[[[3-[2-(dimethylamino)ethyl]-1h-indol-5-yl]methyl]sulfonyl]pyrrolidine, Las 31416, Las-31416 Malate, N,N-Dimethyl-5-[(1-pyrrolidinylsulfonyl)methyl]-1H-indole-3-ethanamine, N,N-dimethyl-2-{5-[(pyrrolidin-1-ylsulfonyl)methyl]-1H-indol-3-yl}ethanamine, Pyrrolidine, 1-[[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]sulfonyl]-, Almotriptan

Description

Applications Almotriptan N-Di-methyl Dimer Malate is an impurity of Almotriptan (A575200), which is a serotonin 5HT1B /1D-receptor agonist used for the treatment of migraines.
References Fleishaker, J.C., et al.: Clin. Pharmacol. Ther., 67, 498 (2000), Kamali, F., et al.: Curr. Opin. Cent. Peripher. Nerv. Syst. Invest. Drugs, 2, 197 (2000), Dodick, D.W., et al.: Expert Opin.Pharmacother., 4, 1157 (2003)

• Brand: TRC

Chemical properties

• Molecular weight: 535.74 + (134.09)
• Formula: C₃₀H₄₁N₅O₂S•C₄H₆O₅
• Color/Form: Neat
• InChI: InChI=1S/C30H41N5O2S.C4H6O5/c1-33(2)15-11-24-20-31-28-9-7-22(17-26(24)28)19-30-25(12-16-34(3)4)27-18-23(8-10-29(27)32-30)21-38(36,37)35-13-5-6-14-35;5-2(4(8)9)1-3(6)7/h7-10,17-18,20,31-32H,5-6,11-16,19,21H2,1-4H3;2,5H,1H2,(H,6,7)(H,8,9)
• InChI key: InChIKey=LVFKQIQTBDXZAL-UHFFFAOYSA-N
• SMILES: CN(C)CCc1c[nH]c2ccc(Cc3[nH]c4ccc(CS(=O)(=O)N5CCCC5)cc4c3CCN(C)C)cc12.O=C(O)CC(O)C(=O)O