Product Information
Name:Almotriptan Malate N-Oxide
Controlled Product
Synonyms:
- N,N-dimethyl-2-(5-((pyrrolidin-1-ylsulfonyl)methyl)-1H-indol-3-yl)ethanamine Oxide,Almotriptan Malate Impurity D
Brand:TRC
Description:Applications Almotriptan Malate N-Oxide is a metabolite of Almotriptan (A575200), which is a serotonin 5HT1B /1D-receptor agonist used for treatment of migraine.References Fleishaker, J.C., et al.: Clin. Pharmacol. Ther., 67, 498 (2000), Kamali, F., et al.: Curr. Opin. Cent. Peripher. Nerv. Syst. Invest. Drugs, 2, 197 (2000), Dodick, D.W., et al.: Expert Opin.Pharmacother., 4, 1157 (2003)
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Chemical properties
Molecular weight:351.46 + 134.09
Formula:C17H25N3O3S•C4H6O5
Color/Form:Neat
InChI:InChI=1S/C17H25N3O3S.C4H6O5/c1-20(2,21)10-7-15-12-18-17-6-5-14(11-16(15)17)13-24(22,23)19-8-3-4-9-19;5-2(4(8)9)1-3(6)7/h5-6,11-12,18H,3-4,7-10,13H2,1-2H3;2,5H,1H2,(H,6,7)(H,8,9)
SMILES:C[N+](C)([O-])CCc1c[nH]c2ccc(CS(=O)(=O)N3CCCC3)cc12.O=C(O)CC(O)C(=O)O
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