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Acetoxy Ticagrelor Acetonide

CAS:

Ref. TR-A445310

5mg
256.00€
10mg
456.00€
25mg
1,031.00€
Acetoxy Ticagrelor Acetonide
TRC

    Product Information

    Name:Acetoxy Ticagrelor Acetonide
    Controlled Product
    Synonyms:
    • 2-(((3aR,4S,6R,6aS)-6-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethyl Acetate
    Brand:TRC
    Description:Applications Acetoxy Ticagrelor Acetonide is an intermediate in the synthesis of Ticagrelor Acetoxide (D232265) which is an acetoxy impurity of Ticagrelor (T437700). Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)
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    Chemical properties

    Molecular weight:604.67
    Formula:C28H34F2N6O5S
    Color/Form:Neat
    InChI:InChI=1S/C28H34F2N6O5S/c1-5-10-42-27-32-25(31-19-12-16(19)15-6-7-17(29)18(30)11-15)22-26(33-27)36(35-34-22)20-13-21(39-9-8-38-14(2)37)24-23(20)40-28(3,4)41-24/h6-7,11,16,19-21,23-24H,5,8-10,12-13H2,1-4H3,(H,31,32,33)/t16-,19+,20+,21-,23-,24+/m0/s1
    InChI key:InChIKey=NLSOWKSOHDESKM-MCHVBHGGSA-N
    SMILES:CCCSc1nc(N[C@@H]2C[C@H]2c2ccc(F)c(F)c2)c2nnn([C@@H]3C[C@H](OCCOC(C)=O)[C@H]4OC(C)(C)O[C@H]43)c2n1

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